第18卷第7期 2010年7月
文章编号1004-924X(2010)07-1562-06
光学精密工程
Optics and Precision Engineering
Vol. 18No.7
Jul. 2010
亲/疏水性不同壁面组成微通道的深宽比
与通道内液体的自发毛细流动
邓永波1.2，张平1.3，杜新1.2，吴一辉1,3，刘震字1，刘永顺1,3
（1.中国科学院长春光学精密机械与物理研究所应用光学国家重点实验室，吉林长春130033；
2.中国科学院研究生院，北京100039；3.中国科学院苏州生物医学工程技术研究所，江苏苏州215163）摘要：研究了案合物芯片上由亲/疏水性不同壁面组成的微通道内流体的流动行为。为了实现该类微通道内液体的自发毛细流动和被操作液体的自发毛细输运，根据系统总表面自由能极小原理，提出了微通道内毛细输运自发实现时微通道的临界深宽比条件。在以二聚二甲基硅氧烷(PDMS)和玻璃为材料的微流控芯片上进行了三面蔬水一面亲水微通道内水的毛细输运实验。针对165μm，200μm和265μm3种深度的通道，理论计算的临界深宽比为0.5，而实验得到的值分别为0.4714，0.4878和0.4818，实验结果与理论预测结果基本相符，从而验证了由亲疏水性不间的壁面组成的微通道内毛细输运自发实现的临界深宽比条件。
关键调：聚合物芯片；微通道；深宽比；PDMS；玻璃
中图分类号：TN305;TP391.4
文献标识码：A
doi;10,3788/OPE,20101807.1562
Aspectratioformicrochannelswithnonuniform surfacepropertiesandspontaneouscapillary
DENG Yong-bo",ZHANG Ping'-,DU Xin'-2 WU Yi-hui-s,LIU Zhen-yu',LIU Yong-shun'-s
(l.StateKeyLaboratory of AppliedOptics,Changchun Institute of Optics,
FineMechanics and Physics,Chinese Academy of Sciences,Changchun 130033,China; 2.GraduateUniversity of ChineseAcademy of Sciences,Beijing 100039,China;
3. Suzhou Institute of Biomedical Engineering and Technology,Chinese Academy of Sciences,Suchou 215163,China) Abstract: The flow characteristics of the fluid in microchannels formed by different hydrophobic and hydrophilic walls on the polymeric microfluidic chips were researched in this study. To achieve the spontaneous capillary of the liquid in a microchannel, the aspect ratio condition of the microchannels for the smoothing capillary was proposed on the basis of the free energy minimization approach. The experiments of the capillary transportation in the microchannels with three Polydimelhysiloxane(PDMS) walls and one glass wall were performed to confirm the aspect ratio condition. According to proposed theory, the critical aspect ratio of the microchannels with the depths 165 μm, 200 μm and 265 μm is 0. 5000. In our experiment, the critical aspect ratios are 0. 4714,0. 4878 and 0. 4818 respec
收稿日期：2009-08-22；修订日期：2009-09-30
基金项目：国家863高技术研究发展计划B类资助项目（No.2006AA04Z367)；国家863高技术研究发展计划重点
资助项目（No.2007AA042102，No.2006AA042358）