2017年第36卷第7期综述与专论
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CHEMICALINDUSTRYAND ENGINEERINGPROGRESS
蛋白基表面活性剂的合成、性能与应用进展汪保川1.2，李字鹏1.2，戴国琛1.2，李正军1.2，杨秦欢3
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（"四川大学制革清洁技术国家工程实验室，四川成都610065：2四川大学皮革化学与工程教育部重点实验室
四川成都610065；"精细化工助剂及表面活性剂四川省高校重点实验室，四川自贡643000）
摘要：蛋白基表面活性剂是一类环境友好的生物质基表面活性剂，具有良好的表面活性，与传统表面活性剂相比，还具有低毒、易生物降解等特性。本文首先讨论了基于胶原蛋白、丝蛋白、角蛋白等动物蛋白水解物制备表面活性剂的方法，其中重点阐述了分子量和水解方法对作为表面活性剂亲水端的胶原蛋白水解物性质的影响，以及分别以脂肪碳链和硅氧烷链为疏水端的胶原基表面活性剂的合成方法。随后，总结并比较了蛋白基表面活性剂的表面张力、临界胶束浓度、起泡力和乳化力等表面性质。依据蛋白基表面活性剂的表面性质和环境友好等特性，介绍了它们在制革印染、日用化工、生物医药等领域的应用。最后，指出了蛋白基表面活性剂制备和
应用中存在的一些间题，对新型表面活性剂（如Bola型、Gemini型）发展方向进行了展望。关键词：胶原：角蛋白：丝蛋白：表面活性剂：合成
中图分类号：TQ423
文献标志码：A
DOI: 10.16085/j.issn.1000-6613.2016-2275
文章编号：1000-6613（2017）07-2607-08
Synthesis，propertiesandapplicationofproteinbasedsurfactants:a
review
WANG Baochuan'-2, LI Yupeng'. 2,DAI Guochenl.2,LI Zhengjun'-2,YANG Qinhuan(' National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu
610065, Sichuan, China; "The Key Laboratory of Leather Chemistry and Engineering of Ministry of Education, Sichuar University, Chengdu 610065, Sichuan, China; "Key Laboratories of Fine Chemicals and Surfactants in Sichuan Provincial
Universities,Zigong 643000,Sichuan，China）
Abstract:Protein based surfactants, a class of environmental-friendly biomass-based surfactants possess excellent surface active properties and particular performances including low toxicity and easy biodegradability compared with traditional surfactants. This article firstly discussed the methods of synthesizing protein based surfactants, based on hydrolysates of animal proteins such as collagen, silk protein and keratin. This part was focused on the influence of molecular weight and hydrolysis methods on the properties of collagen hydrolysate as hydrophilic domains, and methods for preparing collagen based surfactants using hydrocarbon chain or siloxane chain as hydrophobic domains. Then, their surface properties were summarized and compared, such as surface tension,critical micell concentration, foaming and emulsifying properties. And the diverse applications in the fields of leather manufacturing, printing and dyeing, daily chemicals and biological medicine were also introduced on the basis of their surface properties and environmental-friendly features. Finally,some issues of preparation and application of protein based surfactants were pointed out, and in particular the developing
收稿日期：2016-12-08：修改稿日期：2017-03-01。
基金项目：精细化工助剂及表面活性剂四川省高校重点实验室开放基
金（2014JXY05）及国家自然科学基金（21376153）项目。万方数据
第一作者：注保川（1992—），女，硕±研究生，E-mail：286516744@ qq.com。联系人：李正军，教授。E-mail；lizhengjun@scu.edu.cn，